HCID 86706491, compound → HCID 86706490, compound

Participants

Reaction Steps

Ethyl 3-(benzyloxy)-1-{3-[(tert-butoxycarbonyl)amino]propyl}-1H-pyrazole-5-carboxylate (7 g, 17.4 mmol) was dissolved in a 4 M solution of HCl in 1,4-dioxane (50 mL). The mixture was stirred at room temperature for 1 hour and then the solvent was evaporated in vacuo to yield ethyl 3-(benzyloxy)-1-[3-amino-propyl]-1H-pyrazole-5-carboxylate (5.5 g, 95% yield) that was used in the next step without further purification.

Provenance & Evidence