HCID 68963802, compound → HCID 136387221, compound

Participants

Reaction Conditions

Reaction Steps

3-(4-Benzyloxy-3,5-dichloro-phenyl)-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-6-ylamine (0.2 g, 0.500 mmol) is dissolved in 48% HBr in water (20 ml) and heated to 120° C. for 1 hour. The reaction mixture is cooled to room temperature and the resulting precipitate is collected by filtration and re-crystallised from EtOH to afford the title compound.

Provenance & Evidence