HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → HCID 56973649, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | 4-Bromo-2,6-difluorobenzonitrile | HCID 2756916 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 56973649 | HCID 56973649 | — |
Reaction Steps
5.0 g (22.9 mmol) 4-bromo-2,6-difluorobenzonitrile in 200 ml of a solution of NH3 in ethanol and heated in a pressure vessel to 90° C. for 20 h. After cooling to RT the solvent is evaporated and the residue taken up in water/DCM. The organic phase is separated, dried and evaporated.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08901138B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-592d1687910c4f5ebc77d279a5c7656a |
| Source note | uspto-grants-2014_12 |