Hydrochloric Acid → HCID 86701161, compound

Participants

Reaction Steps

To a mixture of 3.74 g of methyl 4-(tert-butylamino)-5-nitro-2-vinylbenzoate and 37.4 mL of methanol was added 21.7 mL of 6 M hydrochloric acid, followed by heating to reflux for 1 hour. The reaction mixture was cooled to room temperature and the precipitated solid was collected by filtration. The obtained solid was dried at 40° C. for 2 hours under reduced pressure to obtain 2.56 g of methyl 4-amino-5-nitro-2-vinylbenzoate monohydrochloride as a yellow solid.

Provenance & Evidence