Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 2-(4-Chlorophenoxy)-1-(piperazin-1-yl)ethanone | HCID 1074760 | — |
| Reactant | 4-Chloro-6-(4-fluorophenyl)thieno[2,3-d]pyrimidine | HCID 86662441 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 56941754 | HCID 56941754 | — |
Reaction Steps
To a solution of 4-chloro-6-(4-fluorophenyl)thieno[2,3-d]pyrimidine (20 mg, 0.08 mmol) and triethylamine (42 μl, 0.3 mmol) in dioxane (1 ml) was added 2-(4-chlorophenoxy)-1-(piperazin-1-yl)ethanone (25 mg, 0.1 mmol). The mixture was heated at 60° C. for 2 hours.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08901132B2 |
|---|
| Source dataset | uspto-grants-2014_12 |
|---|
| ORD ID | ord-9425f8d35de04945b274d49795d732dc |
|---|
| Source note | uspto-grants-2014_12 |
|---|
