反应详情

To a solution of phenylmethyl 2-{(1S)-3-iodo-1-[(methyloxy)carbonyl]propyl}hydrazinecarboxylate (3.38 g, 8.6 mmol) in CH3CN (500 mL) was added K2CO3 (2.38 g, 17.2 mmol), and the mixture was stirred overnight at rt. LC-MS showed that all starting material was consumed. The mixture was filtered, and the filtrate was concentrated to provide the crude 3-methyl 1-(phenylmethyl) (3S)-1,3-pyrazolidinedicarboxylate as an oil (2.77 g, 100%) without further purification.

1. customwas consumed
2. filtrationThe mixture was filtered
3. concentrationthe filtrate was concentrated