Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1397015Generated: October 26, 2026

Boronic Acid → 6-(4-(Trifluoromethyl)phenyl)picolinaldehyde

https://huagongshe.com/reaction/1397015

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBoronic AcidHCID 61668—
Reactant4-(Trifluoromethyl)phenylboronic acidHCID 2734389—
Reactant6-Bromopyridine-2-carbaldehydeHCID 2757009—
Product6-(4-(Trifluoromethyl)phenyl)picolinaldehydeHCID 24730089—

Reaction Steps

6-(4-(trifluoromethyl)phenyl)picolinaldehyde was prepared using the general boronic acid coupling procedure for 6-bromopicolinaldehyde and (4-(trifluoromethyl)phenyl)boronic acid (79 mg, 135.1 mg theoretical, 58.5%). LC-MS m/z 252.2 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08901145B2
Source datasetuspto-grants-2014_12
ORD IDord-fdbe9384890749429f686a89666166b3
Source noteuspto-grants-2014_12