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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1397019Generated: October 30, 2026

Boronic Acid → HCID 86672844, compound

https://huagongshe.com/reaction/1397019

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBoronic AcidHCID 61668—
Reactant2-BromonicotinaldehydeHCID 4714951—
Reactant[5-(Trifluoromethyl)thiophen-2-yl]boronic acidHCID 45158752—
ProductHCID 86672844HCID 86672844—

Reaction Steps

2-(5-(trifluoromethyl)thiophen-2-yl)nicotinaldehyde was prepared using the general boronic acid coupling procedure for 2-bromonicotinaldehyde and (5-(trifluoromethyl)thiophen-2-yl)boronic acid (47.7 mg, 62.3 mg theoretical, 76.6%). LC-MS m/z 258.2 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08901145B2
Source datasetuspto-grants-2014_12
ORD IDord-8f0a7cbd5ed1446687aab463ccfe693c
Source noteuspto-grants-2014_12