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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1397020Generated: November 3, 2026

Boronic Acid → 2-(3-Thienyl)-3-pyridinecarboxaldehyde

https://huagongshe.com/reaction/1397020

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBoronic AcidHCID 61668—
ReactantThiophene-3-boronic acidHCID 581760—
Reactant2-BromonicotinaldehydeHCID 4714951—
Product2-(3-Thienyl)-3-pyridinecarboxaldehydeHCID 2764564—

Reaction Steps

2-(thiophen-3-yl)nicotinaldehyde was prepared using the general boronic acid coupling procedure for 2-bromonicotinaldehyde and thiophen-3-ylboronic acid (60 mg, 101.8 mg theoretical, 58.9%). LC-MS m/z 190.2 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08901145B2
Source datasetuspto-grants-2014_12
ORD IDord-6cc2de8e7a2244b68eaf556dacea9461
Source noteuspto-grants-2014_12