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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1397022Generated: November 2, 2026

Boronic Acid → HCID 86672846, compound

https://huagongshe.com/reaction/1397022

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBoronic AcidHCID 61668—
Reactant1-(tert-Butoxycarbonyl)-2-pyrroleboronic AcidHCID 2734321—
Reactant2-BromonicotinaldehydeHCID 4714951—
ProductHCID 86672846HCID 86672846—

Reaction Steps

tert-butyl 2-(3-formylpyridin-2-yl)-1H-pyrrole-1-carboxylate was prepared using the general boronic acid coupling procedure for 2-bromonicotinaldehyde and (1-(tert-butoxycarbonyl)-1H-pyrrol-2-yl)boronic acid (66 mg, 146.5 mg theoretical, 45.1%). LC-MS m/z 273.3 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08901145B2
Source datasetuspto-grants-2014_12
ORD IDord-bbb3acdac2ca4248aa630774f7c0239b
Source noteuspto-grants-2014_12