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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1397031Generated: November 3, 2026

Boronic Acid → HCID 86672852, compound

https://huagongshe.com/reaction/1397031

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBoronic AcidHCID 61668—
Reactant2-Bromo-4-pyridinecarboxaldehydeHCID 2762991—
Reactant[5-(Trifluoromethyl)thiophen-2-yl]boronic acidHCID 45158752—
ProductHCID 86672852HCID 86672852—

Reaction Steps

2-(5-(trifluoromethyl)thiophen-2-yl)isonicotinaldehyde was prepared using the general boronic acid coupling procedure for 2-bromoisonicotinaldehyde and (5-(trifluoromethyl)thiophen-2-yl)boronic acid (29.4 mg, 62.3 mg theoretical, 47.2%). LC-MS m/z 258.2 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08901145B2
Source datasetuspto-grants-2014_12
ORD IDord-e2ef1f781ab14462bdfb26c676266101
Source noteuspto-grants-2014_12