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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1397033Generated: November 2, 2026

Boronic Acid → HCID 86672854, compound

https://huagongshe.com/reaction/1397033

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBoronic AcidHCID 61668—
Reactant3-(Trifluoromethoxy)phenylboronic Acid (contains varying amounts of Anhydride)HCID 2734385—
Reactant2-BromonicotinaldehydeHCID 4714951—
ProductHCID 86672854HCID 86672854—

Reaction Steps

2-(3-(trifluoromethoxy)phenyl)nicotinaldehyde was prepared using the general boronic acid coupling procedure with 2-bromonicotinaldehyde and (3-(trifluoromethoxy)phenyl)boronic acid (101 mg, 144 mg theoretical, 70.1%). LC-MS m/z 268 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08901145B2
Source datasetuspto-grants-2014_12
ORD IDord-96d6d6bade004b378d7235d65ce636f0
Source noteuspto-grants-2014_12