2-Bromopropiophenone → HCID 24694710, compound

HRID 1397230Notes

Reaction equation

Br[CH:2]([CH3:11])[C:3]([C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1)=O.[C:12]([CH2:14][C:15]([NH2:17])=[S:16])#[N:13]>>[CH3:11][C:2]1[S:16][C:15]([CH2:14][C:12]#[N:13])=[N:17][C:3]=1[C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1

Participants

Reactant 2

HCID 164522-Bromopropiophenone

HCID 14162772-Cyanoethanethioamide

Product 1

HCID 24694710HCID 24694710, compoundYield 56%

Procedure

This compound was synthesized from 2-bromo-1-phenylpropan-1-one and 2-cyanothioacetamide as described in example 1 step 1 (1.7 g, 56% yield %). MS (ESI) m/z: Calculated for C12H10N2S: 214.06. found: 215.0 (M+H)+.

Sources & evidence

ORD record: ord-1881e914784f442eb5f91b66fac8baff
Source dataset: uspto-grants-2014_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08901156B2

Reaction notes

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