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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1397251Generated: November 1, 2026

4-Bromophenacyl bromide → 4-(4-Bromophenyl)-2-thiazoleacetonitrile

https://huagongshe.com/reaction/1397251

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Bromophenacyl bromideHCID 7454—
Reactant2-CyanoethanethioamideHCID 1416277—
Product4-(4-Bromophenyl)-2-thiazoleacetonitrileHCID 279062048%

Reaction Steps

This compound was synthesized from 2-bromo-1-(4-bromophenyl)ethanone and 2-cyanothioacetamide as described in example 1 step 1 (2.4 g, 48% yield), and it was carried through without further purification. MS (ESI) m/z: Calculated for C11H7BrN2S: 277.95. found: 279.0 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08901156B2
Source datasetuspto-grants-2014_12
ORD IDord-4254781229e94dea8ceacebd8ebfc54f
Source noteuspto-grants-2014_12