HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,3-Dichloroacetone → 2-(4-Bromophenyl)-4-(chloromethyl)oxazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,3-Dichloroacetone | HCID 10793 | — |
| Reactant | 4-Bromobenzamide | HCID 69683 | — |
| Product | 2-(4-Bromophenyl)-4-(chloromethyl)oxazole | HCID 15555114 | 14% |
Reaction Steps
This compound was synthesized from 4-bromobenzamide and 1,3-dichloroacetone as described in example 74 step 1 (1.5 g, yield 14%) as a white solid. 1H NMR (400 MHz, CDCl3) δ 7.92-7.89 (d, J=8.8 Hz, 2H), 7.71 (s, 1H), 7.61-7.59 (d, J=8.8 Hz, 2H), 4.57 (s, 2H). MS (ESI) m/z: Calculated for C10H7BrClNO: 272.94. found: 273.8 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08901156B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-2e72f6c44e4d48ef9329c072765fddcf |
| Source note | uspto-grants-2014_12 |