HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(2-(4-Fluorophenyl)oxazol-4-yl)-2-methylpropan-1-amine → HCID 69950218, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(2-(4-Fluorophenyl)oxazol-4-yl)-2-methylpropan-1-amine | HCID 67323086 | — |
| Reactant | 5-(5-(Trifluoromethyl)-1,2,4-oxadiazol-3-yl)nicotinic acid | HCID 67324216 | — |
| Product | HCID 69950218 | HCID 69950218 | 13% |
Reaction Steps
This compound was synthesized from 2-(2-(4-fluorophenyl)oxazol-4-yl)-2-methylpropan-1-amine and 5-(5-trifluoromethyl-[1,2,4]oxadiazol-3-yl)-nicotinic acid as described in example 8 step 6 (19 mg, yield 13%). 1H NMR (400 MHz, MeOD) δ 9.38 (d, J=1.5 Hz, 1H), 9.17 (d, J=1.8 Hz, 1H), 8.84 (d, J=1.8 Hz, 1H), 8.09-8.05 (m, 2H), 7.78 (s, 1H), 7.25-7.20 (m, 2H), 3.68 (s, 2H), 1.42 (s, 6H). MS (ESI) m/z: Calculated for C22H17F4N5O3: 475.13. found: 476.2 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08901156B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-9209f95a57114b899771d7ee554138f6 |
| Source note | uspto-grants-2014_12 |