HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(2-phenyl-1,3-oxazol-4-yl)ethan-1-amine → HCID 67344658, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(2-phenyl-1,3-oxazol-4-yl)ethan-1-amine | HCID 18071418 | — |
| Reactant | 3-(5-(Trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzoic acid | HCID 25180854 | — |
| Product | HCID 67344658 | HCID 67344658 | 25% |
Reaction Steps
This compound was synthesized from 2-(2-phenyloxazol-4-yl)ethanamine and 3-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzoic acid as described in example 8 step 6 (40 mgs, yield 25%). 1H NMR (CDCl3) δ 8.59 (s, 1H), 8.26 (d, J=7.8 Hz, 1H), 8.13 (d, J=8.1 Hz, 1H), 8.05 (m, 2H), 7.62-7.56 (m, 3H), 7.43 (m, 2H), 3.84 (m, 2H), 2.93 (m, 2H). MS (ESI) m/z: Calculated for C21H15F3N4O3: 428.11. found: 429.1 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08901156B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-8552ad4c90a54020b717f6455943bfc6 |
| Source note | uspto-grants-2014_12 |