HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(2-phenyl-1,3-oxazol-4-yl)ethan-1-amine → HCID 67349844, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(2-phenyl-1,3-oxazol-4-yl)ethan-1-amine | HCID 18071418 | — |
| Reactant | 5-(5-(Trifluoromethyl)-1,2,4-oxadiazol-3-yl)nicotinic acid | HCID 67324216 | — |
| Product | HCID 67349844 | HCID 67349844 | 32% |
Reaction Steps
This compound was synthesized from 2-(2-phenyloxazol-4-yl)ethanamine and 5-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)nicotinic acid as described in example 8 step 6 (42 mgs, yield 32%). 1H NMR (CDCl3) δ 9.46 (d, J=2.1 Hz, 1H), 9.32 (d, J=2.1 Hz, 1H), 8.87 (t, J=2.7 Hz, 1H), 8.06-7.96 (m, 3H), 7.57-7.44 (m, 3H), 3.85 (m, 2H), 2.93 (t, J=6.3 Hz, 2H). MS (ESI) m/z: Calculated for C20H14F3N5O3: 429.10. found: 430.1 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08901156B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-fc35eaa4178e4a668b09cbb18b2601be |
| Source note | uspto-grants-2014_12 |