Hydrochloric Acid → HCID 67325165, compound

Participants

Reaction Steps

A sodium hydroxide solution (0.2 mL, 5 M) was added to a solution of methyl 3-(3-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzamido)propanoate in THF/MeOH/water (4:1:1, 15 mL). The reaction was stirred for 30 min and acidified with 2 M HCl. The reaction was extracted with ethyl acetate several times, dried over sodium sulfate, and used crude. MS (ESI) m/z: Calculated for C13H10F3N3O4: 329.06. found: 330.1 (M+H)+.

Provenance & Evidence