Dimethylformamide → 3-(1,1-Dimethylethyl)-4-(1-pyrrolidinyl)benzaldehyde

HRID 139792Notes

Reaction equation

HRID 139792 reaction equation
[Br:1][c:2]1[cH:3][c:4]([C:13]([CH3:14])([CH3:15])[CH3:16])[c:5]([N:8]2[CH2:9][CH2:10][CH2:11][CH2:12]2)[cH:6][cH:7]1.[CH2:17]([Li:18])[CH2:19][CH2:20][CH3:21].[O:22]=[CH:23][N:24]([CH3:25])[CH3:26]>>[c:2]1([CH:23]=[O:22])[cH:3][c:4]([C:13]([CH3:14])([CH3:15])[CH3:16])[c:5]([N:8]2[CH2:9][CH2:10][CH2:11][CH2:12]2)[cH:6][cH:7]1

Participants

4

Reactant 3

HCID 6228DimethylformamideHCID 666722611-(4-Bromo-2-tert-butyl-phenyl)-pyrrolidineHCID 178418339Butyllithium

Product 1

HCID 860427013-(1,1-Dimethylethyl)-4-(1-pyrrolidinyl)benzaldehyde

Sources & evidence

ORD record
ord-51db0403c0204c3381f76d681ae70c6e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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