HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 86722011, compound → HCID 136253053, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 86722011 | HCID 86722011 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 136253053 | HCID 136253053 | 100% |
Reaction Steps
Palladium on carbon catalyst (5%, 400 mg) and 5-(4-(benzyloxy)phenyl)-1-(2-methoxyphenyl)-3-(2,2,6,6-tetramethyltetrahydro-2H-pyran-4-yl)-1H-pyrazole (257.8 mg, 0.52 mmol) were taken in MeOH (10 mL) and stirred under a H2 atmosphere (balloon) for 18 h. The catalyst was removed by filtration and the solvent was removed under vacuum to give 211 mg (100%) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08901314B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-a5abdf9b99e84b73850504ffba7acf12 |
| Source note | uspto-grants-2014_12 |