HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,2-Dichloroethane → 366452-03-1
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,2-Dichloroethane | HCID 11 | — |
| Reactant | 4-Coumaric acid | HCID 322 | — |
| Reactant | 5-Methoxytryptamine | HCID 1833 | — |
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Solvent | Hexane | HCID 8058 | — |
| Product | 366452-03-1 | HCID 636923 | — |
Reaction Steps
(E)-3-(4-hydroxyphenyl)-N-(2-(5-methoxy-1H-indol-3-yl)ethyl) acrylamide (2h) was synthesized by the condensation of 4-hydroxy cinnamic acid (150 mg, 0.914 mmol) and 5-methoxy tryptamine (207 mg, 1.09 mmol) using standard EDC coupling method. 2h was isolated as yellowish solid (181 mg, 59%) by elution with 25% ethyl acetate in hexane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08901317B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-af7e57e36d904275812d1cc025156f9b |
| Source note | uspto-grants-2014_12 |