Methyl iodide → HCID 178439571, compound

HRID 1399381Notes

Reaction equation

HRID 1399381 reaction equation
[CH2:1]([N:8]1[CH:12]=[C:11]([CH2:13][CH2:14][CH3:15])[N:10]=[N:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[I:16][CH3:17]>>[I-:16].[CH2:1]([N:8]1[CH:12]=[C:11]([CH2:13][CH2:14][CH3:15])[N+:10]([CH3:17])=[N:9]1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 6328Methyl iodide2×HCID 16063410HCID 16063410, compound

Product 1

HCID 178439571HCID 178439571, compound

Conditions

Temperature
40 °C

Procedure

1-benzyl-4-propyl-1H-1,2,3-triazole prepared above and excess iodomethane were added to a 20 mL vial. The reaction was heated at 40° C. for 3 days. The iodomethane was allowed to evaporate in the hood. The crude product was dissolved with 2 mL CH2Cl2 under reflux. The solution was precipitated into a mixture of acetone, ethyl acetate and hexane and dried in vacuo. The following structure was confirmed:

Workup

  1. additionwere added to a 20 mL vial
  2. customto evaporate in the hood
  3. dissolutionThe crude product was dissolved with 2 mL CH2Cl2
  4. temperatureunder reflux
  5. customThe solution was precipitated into a mixture of acetone, ethyl acetate and hexane
  6. customdried in vacuo

Sources & evidence

ORD record
ord-0c1fe18526954c2d8f7f6f58e891cd05
Source dataset
uspto-grants-2014_12
Patent number
US08906135B1

Reaction notes

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