反应详情

To a solution of 7 (3.0 g, 6.4 mmol) in dichloromethane (50 ml) was added TFA (25 ml) and the mixture was stirred at room temperature for 3 h. The mixture was evaporated to dryness and the crude obtained was purified by chromatography on silica-gel using 5% methanol in chloroform to give Hapten-B (2.1 g, 79%).

1. customThe mixture was evaporated to dryness
2. customthe crude obtained
3. customwas purified by chromatography on silica-gel
4. customto give Hapten-B (2.1 g, 79%)