Dichloromethane → 2-Methyl-2-(3-piperidin-3-yl-phenoxy)-propionic acid benzyl ester

HRID 139962Notes

Reaction equation

HRID 139962 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH:10]([c:14]2[cH:15][c:16]([O:20][C:21]([CH3:22])([CH3:23])[C:24](=[O:25])[O:26][CH2:27][c:28]3[cH:29][cH:30][cH:31][cH:32][cH:33]3)[cH:17][cH:18][cH:19]2)[CH2:11][CH2:12][CH2:13]1)([CH3:5])([CH3:6])[CH3:7].[CH2:34]([Cl:35])[Cl:36].[F:37][C:38]([F:39])([F:40])[C:41]([OH:42])=[O:43]>>[NH:8]1[CH2:9][CH:10]([c:14]2[cH:15][c:16]([O:20][C:21]([CH3:22])([CH3:23])[C:24](=[O:25])[O:26][CH2:27][c:28]3[cH:29][cH:30][cH:31][cH:32][cH:33]3)[cH:17][cH:18][cH:19]2)[CH2:11][CH2:12][CH2:13]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 688845133-[3-(1-Benzyloxycarbonyl-1-methyl-ethoxy)-phenyl]-piperidine-1-carboxylic acid tert-butyl ester

Product 1

HCID 688839562-Methyl-2-(3-piperidin-3-yl-phenoxy)-propionic acid benzyl ester

Sources & evidence

ORD record
ord-3f78e7a39be64f268112f27df9a8857b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

Loading…