HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → 2-(4-(Azepan-1-yl)-6-methyl-2-phenylpyrimidin-5-yl)pentanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Methyl 2-(4-(azepan-1-yl)-6-methyl-2-phenylpyrimidin-5-yl)pentanoate | HCID 66956063 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 2-(4-(Azepan-1-yl)-6-methyl-2-phenylpyrimidin-5-yl)pentanoic acid | HCID 66955200 | 71.7% |
Reaction Steps
This compound was prepared according to general method D from methyl 2-(4-(azepan-1-yl)-6-methyl-2-phenylpyrimidin-5-yl)pentanoate (0.084 g; 0.220 mmol), sodium hydroxide 10N solution (0.220 mL; 2.2 mmol) in methanol (2.2 mL) to afford 0.058 g (69%) of the title compound as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08906906B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-856c450657c14e01a28f6946cb902d5e |
| Source note | uspto-grants-2014_12 |