Sodium Hydroxide → 2-(4-Methyl-6-(4-methylpiperazin-1-yl)-2-phenylpyrimidin-5-yl)pentanoic acid

Participants

Role	Name	HCID	Charge
Reactant	Sodium Hydroxide	HCID 14798	—
Reactant	Methyl 2-(4-methyl-6-(4-methylpiperazin-1-yl)-2-phenylpyrimidin-5-yl)pentanoate	HCID 66955770	—
Solvent	Methanol	HCID 887	—
Product	2-(4-Methyl-6-(4-methylpiperazin-1-yl)-2-phenylpyrimidin-5-yl)pentanoic acid	HCID 66955954	48%

Reaction Steps

This compound was prepared according to general method D from methyl 2-(4-methyl-6-(4-methylpiperazin-1-yl)-2-phenylpyrimidin-5-yl)pentanoate (0.120 g; 0.314 mmol), sodium hydroxide 10N (0.314 mL; 3.14 mmol) in methanol (3 mL) to afford 0.055 g (48%) of the title compound as a white solid.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08906906B2
Source dataset	uspto-grants-2014_12
ORD ID	ord-fd3419389f4640b7a1ca6171af95fd37
Source note	uspto-grants-2014_12