HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → 2-(4-(3,4-Dimethylphenyl)-6-methyl-2-phenylpyrimidin-5-yl)pentanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Methyl 2-(4-(3,4-dimethylphenyl)-6-methyl-2-phenylpyrimidin-5-yl)pentanoate | HCID 66955309 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 2-(4-(3,4-Dimethylphenyl)-6-methyl-2-phenylpyrimidin-5-yl)pentanoic acid | HCID 66956112 | 82.4% |
Reaction Steps
This compound was prepared according to general method D from methyl 2-(4-(3,4-dimethylphenyl)-6-methyl-2-phenylpyrimidin-5-yl)pentanoate (0.083 g; 0.214 mmol), sodium hydroxide 10N (0.214 mL; 2.14 mmol) in methanol (2 mL) to afford 0.066 g (81%) of the title compound as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08906906B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-3c44842358564057af04e4744d7f2a02 |
| Source note | uspto-grants-2014_12 |