HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → 2-[4-Methyl-6-(2-naphthyl)-2-phenyl-pyrimidin-5-yl]pentanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Methyl 2-(4-methyl-6-(naphthalen-2-yl)-2-phenylpyrimidin-5-yl)pentanoate | HCID 66955496 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 2-[4-Methyl-6-(2-naphthyl)-2-phenyl-pyrimidin-5-yl]pentanoic acid | HCID 66955808 | 92.1% |
Reaction Steps
This compound was prepared according to general method D from methyl 2-(4-methyl-6-(naphthalen-2-yl)-2-phenylpyrimidin-5-yl)pentanoate (0.090 g; 0.219 mmol), sodium hydroxide 10N (0.219 mL; 2.19 mmol) in methanol (2 mL) to afford 0.080 g (92%) of the title compound as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08906906B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-0ae9c2cd8a2a48ba88ec88c48836a039 |
| Source note | uspto-grants-2014_12 |