Sodium Hydroxide → 2-(4-(2,3-Dihydrobenzofuran-5-yl)-6-methyl-2-phenylpyrimidin-5-yl)pentanoic acid

Participants

Role	Name	HCID	Charge
Reactant	Sodium Hydroxide	HCID 14798	—
Reactant	Methyl 2-(4-(2,3-dihydrobenzofuran-5-yl)-6-methyl-2-phenylpyrimidin-5-yl)pentanoate	HCID 66955799	—
Solvent	Methanol	HCID 887	—
Product	2-(4-(2,3-Dihydrobenzofuran-5-yl)-6-methyl-2-phenylpyrimidin-5-yl)pentanoic acid	HCID 66955798	92.4%

Reaction Steps

This compound was prepared according to general method D from methyl 2-(4-(2,3-dihydrobenzofuran-5-yl)-6-methyl-2-phenylpyrimidin-5-yl)pentanoate (0.100 g; 0.248 mmol), sodium hydroxide 10N solution (0.248 mL; 2.48 mmol) in methanol (2.5 mL) to afford 0.089 g (91%) of the title compound as a white solid.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08906906B2
Source dataset	uspto-grants-2014_12
ORD ID	ord-2d4fb47014ad4e2b8f1be55062967790
Source note	uspto-grants-2014_12