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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1399639Generated: October 25, 2026

Sodium Hydroxide → 2-(4-(Benzofuran-5-yl)-6-methyl-2-phenylpyrimidin-5-yl)pentanoic acid

https://huagongshe.com/reaction/1399639

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
ReactantMethyl 2-(4-(benzofuran-5-yl)-6-methyl-2-phenylpyrimidin-5-yl)pentanoateHCID 66955366—
SolventMethanolHCID 887—
Product2-(4-(Benzofuran-5-yl)-6-methyl-2-phenylpyrimidin-5-yl)pentanoic acidHCID 6695610985.3%

Reaction Steps

This compound was prepared according to general method D from methyl 2-(4-(benzofuran-5-yl)-6-methyl-2-phenylpyrimidin-5-yl)pentanoate (0.114 g; 0.285 mmol), sodium hydroxide 10N (0.285 mL; 2.85 mmol) in methanol (3 mL) to afford 0.094 g (81%) of the title compound as a white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08906906B2
Source datasetuspto-grants-2014_12
ORD IDord-53a4c86dd932424fb9a5eece3d28da4b
Source noteuspto-grants-2014_12