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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1399649Generated: October 31, 2026

Sodium Hydroxide → HCID 66955372, compound

https://huagongshe.com/reaction/1399649

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
ReactantHCID 66955687HCID 66955687—
SolventMethanolHCID 887—
ProductHCID 66955372HCID 6695537252.8%

Reaction Steps

This compound was prepared according to general method D from methyl 2-(4-(1H-indol-6-yl)-6-methyl-2-phenylpyrimidin-5-yl)pentanoate (0.108 g; 0.270 mmol), sodium hydroxide 10N (0.270 mL; 2.7 mmol) in methanol (2.7 mL). Purification by flash-chromatography on silica gel using a gradient of methanol (1-10%) in dichloromethane furnished 0.055 g (52%) of the title compound as a white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08906906B2
Source datasetuspto-grants-2014_12
ORD IDord-7d9b79fb858440d8952ac01953ab7bb3
Source noteuspto-grants-2014_12