HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → HCID 66955372, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 66955687 | HCID 66955687 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 66955372 | HCID 66955372 | 52.8% |
Reaction Steps
This compound was prepared according to general method D from methyl 2-(4-(1H-indol-6-yl)-6-methyl-2-phenylpyrimidin-5-yl)pentanoate (0.108 g; 0.270 mmol), sodium hydroxide 10N (0.270 mL; 2.7 mmol) in methanol (2.7 mL). Purification by flash-chromatography on silica gel using a gradient of methanol (1-10%) in dichloromethane furnished 0.055 g (52%) of the title compound as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08906906B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-7d9b79fb858440d8952ac01953ab7bb3 |
| Source note | uspto-grants-2014_12 |