HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → 2-(4-Methyl-6-(2-oxoindolin-6-yl)-2-phenylpyrimidin-5-yl)pentanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Methyl 2-(4-methyl-6-(2-oxoindolin-6-yl)-2-phenylpyrimidin-5-yl)pentanoate | HCID 66956203 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 2-(4-Methyl-6-(2-oxoindolin-6-yl)-2-phenylpyrimidin-5-yl)pentanoic acid | HCID 66955527 | 2% |
Reaction Steps
This compound was prepared according to general method D from methyl 2-(4-methyl-6-(2-oxoindolin-6-yl)-2-phenylpyrimidin-5-yl)pentanoate (0.066 g; 0.159 mmol), sodium hydroxide 10N (0.159 mL; 1.59 mmol) in methanol (1.5 mL). Purification by preparative HPLC (HPLC method 2) furnished 0.0012 g (2%) of the title compound as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08906906B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-ade927b3eb244786bd8d3d803fe4733e |
| Source note | uspto-grants-2014_12 |