Sodium Hydroxide → HCID 66955995, compound

HRID 1399673Notes

Reaction equation

HRID 1399673 reaction equation
[CH:1]([C:4]1[CH:9]=[CH:8][C:7]([C:10]2[C:15]([CH:16]([CH2:21][CH2:22][CH3:23])[C:17]([O:19]C)=[O:18])=[C:14]([CH3:24])[N:13]=[C:12]([C:25]3[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=3)[N:11]=2)=[CH:6][CH:5]=1)([CH3:3])[CH3:2].[OH-].[Na+]>CO>[CH:1]([C:4]1[CH:5]=[CH:6][C:7]([C:10]2[C:15]([CH:16]([CH2:21][CH2:22][CH3:23])[C:17]([OH:19])=[O:18])=[C:14]([CH3:24])[N:13]=[C:12]([C:25]3[CH:26]=[CH:27][CH:28]=[CH:29][CH:30]=3)[N:11]=2)=[CH:8][CH:9]=1)([CH3:2])[CH3:3]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 66955343HCID 66955343, compound

Product 1

HCID 66955995HCID 66955995, compoundYield 83.9%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

This compound was prepared according to general method D from methyl 2-(4-(4-isopropylphenyl)-6-methyl-2-phenylpyrimidin-5-yl)pentanoate (0.074 g; 0.184 mmol), sodium hydroxide 10N (0.184 mL; 1.84 mmol) in methanol (2 mL) to afford 0.060 g (83%) of the title compound as a white solid.

Workup

  1. customThis compound was prepared

Sources & evidence

ORD record
ord-0adc4a2392fe4f29b0dd42a4a949add8
Source dataset
uspto-grants-2014_12
Patent number
US08906906B2

Reaction notes

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