Sodium Hydroxide → 4-Methoxy-2-(4-methyl-2-(piperidin-1-yl)-6-p-tolylpyrimidin-5-yl)butanoic acid

Participants

Role	Name	HCID	Charge
Reactant	Sodium Hydroxide	HCID 14798	—
Reactant	Methyl 4-methoxy-2-(4-methyl-2-(piperidin-1-yl)-6-p-tolylpyrimidin-5-yl)butanoate	HCID 50997143	—
Solvent	Methanol	HCID 887	—
Product	4-Methoxy-2-(4-methyl-2-(piperidin-1-yl)-6-p-tolylpyrimidin-5-yl)butanoic acid	HCID 50996972	40.6%

Reaction Steps

This compound was prepared according to general method D from methyl 4-methoxy-2-(4-methyl-2-(piperidin-1-yl)-6-p-tolylpyrimidin-5-yl)butanoate (0.018 g; 0.045 mmol), sodium hydroxide 10N (0.045 mL; 0.45 mmol) in methanol (0.4 mL) to afford 0.007 g (38%) of the title compound as a white solid.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08906906B2
Source dataset	uspto-grants-2014_12
ORD ID	ord-801c8df4a33b4e538085fea8dc8b7d26
Source note	uspto-grants-2014_12