Sodium Hydroxide → 3-Methyl-2-(4-methyl-2-(piperidin-1-yl)-6-p-tolylpyrimidin-5-yl)pentanoic acid

Participants

Role	Name	HCID	Charge
Reactant	Sodium Hydroxide	HCID 14798	—
Reactant	Methyl 3-methyl-2-(4-methyl-2-(piperidin-1-yl)-6-p-tolylpyrimidin-5-yl)pentanoate	HCID 50995546	—
Solvent	Methanol	HCID 887	—
Product	3-Methyl-2-(4-methyl-2-(piperidin-1-yl)-6-p-tolylpyrimidin-5-yl)pentanoic acid	HCID 50995545	74.1%

Reaction Steps

This compound was prepared according to general method D from methyl 3-methyl-2-(4-methyl-2-(piperidin-1-yl)-6-p-tolylpyrimidin-5-yl)pentanoate (0.039 g; 0.099 mmol), sodium hydroxide 10N (0.100 mL; 0.1 mmol) in methanol (1 mL) to afford 0.028 g (73%) of the title compound as a white solid.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08906906B2
Source dataset	uspto-grants-2014_12
ORD ID	ord-c648c8fdddcc424a8ee1b71ae8bf836d
Source note	uspto-grants-2014_12