Sodium Hydroxide → 2-[4-(2,4-Difluorophenyl)-6-methyl-2-(1-piperidyl)pyrimidin-5-yl]pentanoic acid

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Reaction Steps

This compound was prepared according to general method D from methyl 2-(4-(2,4-difluorophenyl)-6-methyl-2-(piperidin-1-yl)pyrimidin-5-yl)pentanoate (0.056 g; 0.139 mmol), sodium hydroxide 10N (0.200 mL; 2.00 mmol) in methanol (2 mL) at 60° C. for 18 h to afford 0.039 g (69%) of the title compound as a white solid.

Provenance & Evidence