HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Sodium Hydroxide → 2-[4-(2,4-Dimethylphenyl)-6-methyl-2-(1-piperidyl)pyrimidin-5-yl]pentanoic acid
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Sodium Hydroxide | HCID 14798 | — |
| Edukt | Methyl 2-(4-(2,4-dimethylphenyl)-6-methyl-2-(piperidin-1-yl)pyrimidin-5-yl)pentanoate | HCID 66955327 | — |
| Lösungsmittel | Methanol | HCID 887 | — |
| Produkt | 2-[4-(2,4-Dimethylphenyl)-6-methyl-2-(1-piperidyl)pyrimidin-5-yl]pentanoic acid | HCID 50995730 | 89,3% |
Reaktionsschritte
This compound was prepared according to general method D from 2 methyl 2-(4-(2,4-dimethylphenyl)-6-methyl-2-(piperidin-1-yl)pyrimidin-5-yl)pentanoate (0.073 g; 0.185 mmol), sodium hydroxide 10N (0.200 mL; 2.00 mmol) in methanol (2 mL) at 60° C. for 18 h to afford 0.063 g (88%) of the title compound as a white solid.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08906906B2 |
| Quelldatensatz | uspto-grants-2014_12 |
| ORD ID | ord-463eccf03c934df99f3eea72574f7ce1 |
| Quellennotiz | uspto-grants-2014_12 |