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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1399772Generated: October 30, 2026

2-(5-Chlorochroman-6-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane → Methyl 2-(4-(5-chlorochroman-6-yl)-6-methyl-2-(piperidin-1-yl)pyrimidin-5-yl)pentanoate

https://huagongshe.com/reaction/1399772

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(5-Chlorochroman-6-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolaneHCID 59606763—
ReactantMethyl 2-(4-chloro-6-methyl-2-(piperidin-1-yl)pyrimidin-5-yl)pentanoateHCID 86665653—
ProductMethyl 2-(4-(5-chlorochroman-6-yl)-6-methyl-2-(piperidin-1-yl)pyrimidin-5-yl)pentanoateHCID 66955735—

Reaction Steps

This compound is prepared according to general method E starting from methyl 2-(4-chloro-6-methyl-2-(piperidin-1-yl)pyrimidin-5-yl)pentanoate and 2-(5-chlorochroman-6-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08906906B2
Source datasetuspto-grants-2014_12
ORD IDord-451349e9879e4a7da5409bb5ee6c02be
Source noteuspto-grants-2014_12