HCID 86696912, compound → HCID 86696911, compound

HRID 1400001Notes

Reaction equation

C([O:3][CH:4](OCC)[C:5]1[N:6]=[N:7][N:8]([C:10]2[CH:11]=[C:12]([C:29]3[CH:34]=[CH:33][CH:32]=[CH:31][N:30]=3)[C:13]3[S:17][C:16]([N:18]4CN(C)C[N:20]([CH2:25][CH3:26])[C:19]4=[O:27])=[N:15][C:14]=3[CH:28]=2)[CH:9]=1)C>Cl>[CH2:25]([NH:20][C:19]([NH:18][C:16]1[S:17][C:13]2[C:12]([C:29]3[CH:34]=[CH:33][CH:32]=[CH:31][N:30]=3)=[CH:11][C:10]([N:8]3[CH:9]=[C:5]([CH:4]=[O:3])[N:6]=[N:7]3)=[CH:28][C:14]=2[N:15]=1)=[O:27])[CH3:26]

Participants

Conditions

Temperature: 70 °C

Procedure

Compound iii (250 mg, 0.48 mmol) was suspended in 1M HCl solution (9 mL) and the mixture heated at 70° C. overnight. The mixture was concentrated in vacuo to give iv (213 mg, quantitative). MS: 394.0 [M+H]+.

Workup

concentrationThe mixture was concentrated in vacuo

Sources & evidence

ORD record: ord-4e71e7edab364c13bbc2dfd2a27211e6
Source dataset: uspto-grants-2014_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08906902B2

Reaction notes

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