Tert-Butylamine → HCID 52938817, compound
Reaction equation
[NH2:1][C:2]1[N:11]=[C:10]([C:12]([N:14]2[CH2:22][C:21]3[C:16](=[CH:17][CH:18]=[CH:19][CH:20]=3)[CH2:15]2)=[O:13])[C:9]2[C:4](=[CH:5][CH:6]=[C:7]([C:23]3([C:27](O)=[O:28])[CH2:26][CH2:25][CH2:24]3)[CH:8]=2)[N:3]=1.[C:30]([NH2:34])([CH3:33])([CH3:32])[CH3:31]>>[NH2:1][C:2]1[N:11]=[C:10]([C:12]([N:14]2[CH2:15][C:16]3[C:21](=[CH:20][CH:19]=[CH:18][CH:17]=3)[CH2:22]2)=[O:13])[C:9]2[C:4](=[CH:5][CH:6]=[C:7]([C:23]3([C:27]([NH:34][C:30]([CH3:33])([CH3:32])[CH3:31])=[O:28])[CH2:24][CH2:25][CH2:26]3)[CH:8]=2)[N:3]=1Participants
3
Procedure
(Preparation by reaction of 1-[2-amino-4-(isoindoline-2-carbonyl)quinazolin-6-yl]cyclobutanecarboxylic acid [“A61”] with tert-butylamine)
Sources & evidence
- ORD record
- ord-993b803b755642f7b505dec72a375a95
- Source dataset
- uspto-grants-2014_12
- Patent number
- US08906930B2
Reaction notes
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