Tert-Butylamine → HCID 52938942, compound

HRID 1400125Notes

Reaction equation

HRID 1400125 reaction equation
[NH2:1][C:2]1[N:11]=[C:10]([C:12]([N:14]2[CH2:22][C:21]3[C:16](=[CH:17][CH:18]=[CH:19][CH:20]=3)[CH2:15]2)=[O:13])[C:9]2[C:4](=[CH:5][CH:6]=[C:7]([C:23]([CH3:28])([CH3:27])[C:24]([OH:26])=O)[CH:8]=2)[N:3]=1.[C:29]([NH2:33])([CH3:32])([CH3:31])[CH3:30]>>[NH2:1][C:2]1[N:11]=[C:10]([C:12]([N:14]2[CH2:15][C:16]3[C:21](=[CH:20][CH:19]=[CH:18][CH:17]=3)[CH2:22]2)=[O:13])[C:9]2[C:4](=[CH:5][CH:6]=[C:7]([C:23]([CH3:27])([CH3:28])[C:24]([NH:33][C:29]([CH3:32])([CH3:31])[CH3:30])=[O:26])[CH:8]=2)[N:3]=1

Participants

3

Reactant 2

HCID 6385Tert-ButylamineHCID 52939428HCID 52939428, compound

Product 1

HCID 52938942HCID 52938942, compound

Procedure

(Preparation by reaction of 2-[2-amino-4-(isoindoline-2-carbonyl)quinazolin-6-yl]-2-methylpropanoic acid [“A62”] with tert-butylamine);

Sources & evidence

ORD record
ord-daa3297fa7cc4e4289f953f69ec9c211
Source dataset
uspto-grants-2014_12
Patent number
US08906930B2

Reaction notes

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