反应详情

温度

23 °C

11.3 g of ethyl 1-(4-nitrophenyl)cyclopropanecarboxylate are dissolved in 110 ml of tetrahydrofuran, 1 g of 5% Pd/C (52.3% of water) is added, and the mixture is stirred at 23° C. under a hydrogen atmosphere for 1 h. After aeration, the solid material is filtered off, and the filtrate is evaporated to dryness in vacuo. Yield: 9.8 g (100%) of ethyl 1-(4-aminophenyl)cyclopropanecarboxylate; LC-MS retention time: 1.18 min (“nonpolar” gradient).

1. filtrationAfter aeration, the solid material is filtered off
2. customthe filtrate is evaporated to dryness in vacuo