Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Tetrahydrofuran | HCID 8028 | — |
| Reactant | HCID 67154002 | HCID 67154002 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Product | HCID 67153997 | HCID 67153997 | — |
Reaction Steps
2.6 g of 2-methyl-2-(4-nitrophenyl)pentanoic acid are dissolved in 30 ml of tetrahydrofuran, 1 g of 5% Pd/C (52.3% of water) is added, and the mixture is stirred at 23° C. under a hydrogen atmosphere for 1 h. After aeration, the solid material is filtered off, and the filtrate is evaporated to dryness in vacuo. Yield: 2.2 g (95%) of ethyl 2-(4-aminophenyl)-2-methylpropanoate; LC-MS retention time: 1.99 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08906930B2 |
|---|
| Source dataset | uspto-grants-2014_12 |
|---|
| ORD ID | ord-3209ae0b067444d8866e4064590f2dd6 |
|---|
| Source note | uspto-grants-2014_12 |
|---|
