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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1400166Generated: October 30, 2026

Trifluoroacetic acid → HCID 67154034, compound

https://huagongshe.com/reaction/1400166

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 68227620HCID 68227620—
SolventDichloromethaneHCID 6344—
ProductHCID 67154034HCID 67154034—

Reaction Conditions

Temperature23 °C

Reaction Steps

200 μl of trifluoroacetic acid are added to 100 mg of O1-tert-butyl O5-ethyl 4-[2-amino-4-(isoindoline-2-carbonyl)quinazolin-6-yl]-2-methylenepentanedioate in 1 ml of dichloromethane, and the mixture is stirred at 23° C. for 3 h. The mixture is subsequently evaporated to dryness in vacuo and reacted further directly.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08906930B2
Source datasetuspto-grants-2014_12
ORD IDord-2539bd1014ce4e798f17331c5eb6fb67
Source noteuspto-grants-2014_12