Furfural → HCID 68151378, compound

HRID 1400268Notes

Reaction equation

[Cl-].[Cl:2][C:3]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[CH:6]=[CH:5][C:4]=1[S:13][CH2:14][CH2:15][NH3+:16].[O:17]1[CH:21]=[CH:20][CH:19]=[C:18]1[CH:22]=O>>[Cl:2][C:3]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[CH:6]=[CH:5][C:4]=1[S:13][CH2:14][CH2:15][NH:16][CH2:22][C:18]1[O:17][CH:21]=[CH:20][CH:19]=1

Participants

Reactant 2

HCID 7362Furfural

HCID 68151503HCID 68151503, compound

Product 1

HCID 68151378HCID 68151378, compoundYield 57%

Procedure

The reductive amination step of 2-[(1-chloronaphthalen-2-yl)sulfanyl]ethanaminium chloride with furan-2-carbaldehyde was performed as described for compound I to obtain 2-[(1 chloronaphthalen-2-yl)sulfanyl]-N-(furan-2-ylmethyl)ethanamine in 57% yield.

Sources & evidence

ORD record: ord-f23290d1b2a1452c83d5028bf5d1775f
Source dataset: uspto-grants-2014_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08906946B2

Reaction notes

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