Furfural → HCID 59053465, compound

HRID 1400275Notes

Reaction equation

HRID 1400275 reaction equation
[Cl:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH:5]=[CH:4][C:3]=1[CH2:12][CH2:13][CH2:14][NH2:15].[O:16]1[CH:20]=[CH:19][CH:18]=[C:17]1[CH:21]=O>>[Cl:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH:5]=[CH:4][C:3]=1[CH2:12][CH2:13][CH2:14][NH:15][CH2:21][C:17]1[O:16][CH:20]=[CH:19][CH:18]=1

Participants

3

Reactant 2

HCID 7362FurfuralHCID 68151387HCID 68151387, compound

Product 1

HCID 59053465HCID 59053465, compoundYield 45%

Procedure

The reductive ammination of 3-(1-chloronaphthalen-2-yl)propan-1-amine and furan-2-carbaldehyde was performed as described for compound I to obtain the compound as a pale yellow oil (45% yield).

Sources & evidence

ORD record
ord-dc53394e959347fa86b236a6102ff7d4
Source dataset
uspto-grants-2014_12
Patent number
US08906946B2

Reaction notes

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