2-Pyridinecarboxaldehyde → N-(1-chloronaphthalen-2-yl)-N'-(pyridin-2-ylmethyl)ethane-1,2-diamine

HRID 1400290Notes

Reaction equation

[Cl-].[Cl:2][C:3]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[CH:6]=[CH:5][C:4]=1[NH:13][CH2:14][CH2:15][NH3+:16].[N:17]1[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=1[CH:23]=O>>[Cl:2][C:3]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[CH:6]=[CH:5][C:4]=1[NH:13][CH2:14][CH2:15][NH:16][CH2:23][C:18]1[CH:19]=[CH:20][CH:21]=[CH:22][N:17]=1

Participants

Reactant 2

HCID 142732-Pyridinecarboxaldehyde

HCID 68152103HCID 68152103, compound

Product 1

HCID 59053595N-(1-chloronaphthalen-2-yl)-N'-(pyridin-2-ylmethyl)ethane-1,2-diamineYield 52%

Procedure

Prepared from 2-[(1-chloronaphthalen-2-yl)amino]ethanaminium chloride and pyridine-2-carbaldehyde in 52% yield as a yellow oil.

Sources & evidence

ORD record: ord-1fdce21cbe944a3ea61945fc6e3c36a3
Source dataset: uspto-grants-2014_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08906946B2

Reaction notes

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