HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Chlorothiophene-2-carbaldehyde → 5-Chloro-6-(2-{[(5-chlorothiophen-2-yl)methyl]amino}ethoxy)naphthalene-2-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Chlorothiophene-2-carbaldehyde | HCID 2735825 | — |
| Reactant | 2-[(1-Chloro-6-cyanonaphthalen-2-yl)oxy]ethanaminium chloride | HCID 68151287 | — |
| Product | 5-Chloro-6-(2-{[(5-chlorothiophen-2-yl)methyl]amino}ethoxy)naphthalene-2-carbonitrile | HCID 59053664 | 63% |
Reaction Steps
Prepared from 2-[(1-chloro-6-cyanonaphthalen-2-yl)oxy]ethanaminium chloride and 5 chlorothiophen-2-carbaldehyde in 63% yield as a yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08906946B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-b848fc7f11fc436182d6e87100212462 |
| Source note | uspto-grants-2014_12 |