HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,2-Dichloroethane → HCID 86710767, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,2-Dichloroethane | HCID 11 | — |
| Reactant | HCID 89971438 | HCID 89971438 | — |
| Catalyst | (1,3-Bis(2,4,6-trimethylphenyl)imidazolidin-2-ylidene)(dichloro)((2-((propan-2-yl)oxy)phenyl)methylidene)ruthenium | HCID 11763533 | — |
| Product | HCID 86710767 | HCID 86710767 | — |
Reaction Steps
A solution of (2S)-methyl 2-(7-(4-allylchroman-6-yl)-2-(2′-(but-3-en-1-yl)-[1,1′-biphenyl]-3-yl)-5-methylpyrazolo[1,5-a]pyrimidin-6-yl)-2-(tert-butoxy)acetate (0.054 g, 0.082 mmol) in DCE (5.0 mL) was heated (70° C.), then treated with Hoveyda-Grubbs Cat. 2nd Gen. (5 mg, 8 μmol). The reaction was stirred for 90 min. The reaction was cooled, then concentrated and the residue was used immediately in the following step. LCMS (M+H)=628.4.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08906929B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-fba07feb289d4b968f495bdf3bcbedeb |
| Source note | uspto-grants-2014_12 |